ONCOmmunity

Prognostic Impact of Geriatric Nutritional Risk Index in Patients With Synchronous Colorectal Liver Metastasis.

By: Tomohiro Iguchi, Keishi Sugimachi, Yohei Mano, Takashi Motomura, Masahiko Sugiyama, Mitsuhiko Ota, Masahiko Ikebe, Taito Esaki, Tomoharu Yoshizumi, Masaru Morita, Masaki Mori, Yasushi Toh

Department of Hepato-Biliary Pancreatic Surgery, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan tomo@surg2.med.kyushu-u.ac.jp.
2020-05-26; doi: 10.21873/anticanres.14416

Abstract

Background/aim

The Geriatric Nutritional Risk Index (GNRI) is a prognostic indicator for several cancers; however, the association between the GNRI and colorectal liver metastasis (CRLM) remains unknown.

Patients

Eighty patients who underwent hepatectomy for synchronous CRLM were divided into two groups based on the GNRI.

Results

The preoperative CA19-9 levels were significantly higher in the low (GNRI ≤98; n=30) than the normal GNRI group (GNRI >98; n=50). Patients in the low GNRI group had poorer outcomes than those in the normal GNRI group. A low GNRI was an independent prognostic factor for recurrence-free survival and overall survival. Among 50 patients who experienced recurrence, only 16 of 22 patients (72.7%) in the low GNRI group could receive intensive treatment and 27 of 28 patients (96.4%) in the normal GNRI group.

Conclusion

The GNRI is a simplified prognostic factor for patients with CRLM.