ONCOmmunity

Clinical Significance of Past History of Breast Cancer Screening for the Prognosis of Triple Negative Breast Cancer.

By: Shingo Inoue, Hiromichi Kawaida, Ryo Saito, Yuko Nakayama, Masato Ohmori, Ayako Kimura, Katsutoshi Shoda, Shinji Furuya, Naohiro Hosomura, Hidenori Akaike, Yoshihiko Kawaguchi, Hidetake Amemiya, Makoto Sudo, Hiroshi Kono, Daisuke Ichikawa

First Department of Surgery, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan shingoi@yamanashi.ac.jp.
2020-12-22; doi: 10.21873/anticanres.14865

Abstract

Background/aim

This study examined the prognostic impact of the past history of breast cancer screening within the last 2 years (PH-BCS), for patients with triple negative breast cancer (TNBC), a subtype that carries extremely poor prognosis.

Patients

Eighty-six consecutive cases with TNBC, who underwent surgery at our faculty from 2009 to 2015, were divided into two groups according to PH-BCS. Prognostic analyses for disease-free survival and overall survival between the two groups were performed.

Results

The positive PH-BCS group (n=44) had a significantly better prognoses than the negative PH-BCS group (n=42) (p<0.001). No recurrent cases were observed in the positive PH-BCS group. In the negative PH-BCS group, tumor and node status and chemotherapy were indicated as significant prognostic factors, and further step-wise multivariate analysis revealed only node status as a significant prognostic factor.

Conclusion

Breast cancer screening at least every 2 years may improve the prognosis of TNBC.