Heavy Alcohol Use Is Associated With Gastric Cancer: Analysis of the National Health and Nutrition Examination Survey From 1999 to 2010.
By: Monika Laszkowska, Steven Rodriguez, Judith Kim, Chin Hur
Division of Digestive and Liver Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA; Department of Medicine, Gastroenterology, Hepatology, and Nutrition Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA; Division of General Medicine, Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York, USA.
2021-2-24; doi: 10.14309/ajg.0000000000001166
2021-2-24; doi: 10.14309/ajg.0000000000001166
Abstract
Introduction
Evidence regarding the association between alcohol use and gastric cancer (GC) has been inconsistent.
Methods
Adults who participated in the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2010 were included. Multivariable regression was used to assess the association between GC and heavy alcohol use (≥5 alcoholic drinks daily).
Results
Of 470,168 individuals surveyed, 342 had a history of GC. Heavy alcohol use was associated with GC (odds ratio 3.13, 95% confidence interval 1.15-8.64) on multivariable analysis.
Discussion
This is the largest study to our knowledge to demonstrate an association between heavy alcohol use and GC in the United States.
Copyright © The American College of Gastroenterology 2021. All Rights Reserved.
PMID:33625123
