Stratification Of CLL By ZAP-70 Expression: Analysis Of Samples From The ECOG-Led Intergroup Trial E2997
Kaplan D, Sun Z, Tallman MS, et al.
Key Points:
The authors report the utility of a powerful flow cytometric amplification system for ZAP-70 expression in CLL patients
ZAP-70 expression exhibited a peak-trough-peak distribution
Using the trough as cut-off, CLL patients can be stratified into 2 different molecular groups with distinct survival outcomes
Implications:
- Tool may be used for providing additional prognostic information in CLL patients.
View the original abstract on the ASH website.
