Outcomes Of Chronic Lymphocytic Leukemia Patients With Richter Syndrome
Parikh SA, Sharma RG, Call TG, et al.
Key Points:
Retrospective analyses determining outcomes in CLL patients who had undergone Richter syndrome (RS) or transformation reported
Average age at diagnosis of RS was 67 years, and majority were males, median time interval between diagnosis of CLL and development of RS: 3.8 years
RS occurred more often in CLL patients with stereotyped B-cell receptors
Median OS noted at 0.9 years
Implications:
- CLL patients with stereotyped B-cell receptors at higher risk of RS and have poor survival outcomes with current therapies
View the original abstract on the ASH website.
