Micafungin Versus Fluconazole Or Itraconazole For Prophylaxis Against Invasive Fungal Infections During Neutropenia In Patients Undergoing Haplo-Identical Hematopoietic Stem Cell Transplantation
Jean E, Roberto C, Sabine F, et al.




Key Points:
  • Retrospective study comparing Micafungin with fluconazole or itraconazole as antifungal prophylaxis for patients undergoing haplo-identical allogeneic stem cell transplantation (haplo-SCT)

  • Micafungin, 50 mg/day administered intravenously, well-tolerated and effective against invasive fungal infection

  • Incidence of invasive aspergillosis and invasive fungal infections appears to be lower with micafungin though N of group was not large enough to be statistically significant

Implications:

  • Micafungin at 50 mg/day in an effective antifungal prophylaxis in haplo-identical allogeneic stem cell transplanted patients

View the original abstract on the ASH website.






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