Bfr (bendamustine, fludarabine, rituximab) Nonmyeloablative Allogeneic Conditioning: A Novel Regimen Inducing Immunosuppression Without Myelosuppression
Khouri IF, Wei W, Valverde R, et al.




Key Points:
  • Safety and efficacy of BFR as non-myeloablative conditioning regimen in patients with lymphoid malignancies investigated

  • Regimen well-tolerated with 1-year treatment-related mortality of 9%

  • Engraftment occurred with minimal myelosuppression

Implications:

  • BFM may represent novel conditioning regimen for allogeneic transplantation in outpatient setting

View the original abstract on the ASH website.






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