Telomere Length and Treatment Outcome In Chronic Lymphocytic Leukemia: Results From The CLL8 Trial
Jebaraj BMC, Busch R, Zenz T, et al.
Key Points:
Impact of telomere length on clinical outcomes in CLL patients explored
Short telomeres associated with high-risk biological features including unmutated IGHV, ZAP70+, del(17p) and del(11q)
Shortened telomere length an independent prognostic marker for poor PFS and OS
Implications:
- Additional studies warranted to validate prognostic implication of short telomeres on clinical outcomes
View the original abstract on the ASH website.
