The Interlaboratory Robustness Of Next-Generation Sequencing (IRON) Study Phase II: Deep-Sequencing Analyses Of Hematological Malignancies Performed In 8,867 Cases By An International Network Involving 27 Laboratories
Kohlmann A, Martinelli G, Alikian M, et al.
Key Points:
Authors report on the design, application and utility of amplicon-based Next Generation Sequencing (NGS) assay in a variety of hematological malignancies
Amplicons for highly-sensitive detection of mutations in 74 selected genes developed
Novel prognostic models based on molecular markers only will be developed
Implications:
- Assay may represent most sensitive and specific test for molecular characterization of various hematological malignancies
View the original abstract on the ASH website.
