Association Of More Than One B Cell Clone Arises In Any Type Of Leukemic Chronic B Cell Disorder
Lazarian G, Roudot H, Farrah R et al.
Key Points:
Overall prognosis and frequency of the biclonal B-cell chronic lymphoproliferative disorders (B-CLPD).
1152 cases of chronic lymphoproliferative disorders selected. Total of 44 cases (3.8%) with at least two B-cell clones detected. Authors found 4 cases with three B-cell clones and 1 case of four clones.
Implications:
- Polyclonal/biclonal B-CLPD observed in less than 5% cases of B cell chronic lymphoproliferative disorders, and not related to an adverse prognosis.
View the original abstract on the ASH website.
