Apparent Involvement Of The Interferon, RNA Processing, and Wnt Signaling Pathways In Monoclonal B Lymphocytosis.
Yan X, Fazi C, Lydia S et al.




Key Points:
  • Study investigated gene expression profiles of normal blood (N) B cells, MBL cells, and CLL cells using microarray technology.

  • Between MBL and N B cells, 1040 genes higher and 868 lower in MBL than N B cells. Genes higher in MBL belong to different categories including “PI3K/AKT Signaling” and “Inflammatory Disease".

Implications:

  • Genes higher in MBL belongs to different categories including “PI3K/AKT Signaling” and “Inflammatory Disease".

View the original abstract on the ASH website.






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