Monitoring Early CMV-Specific CD8+ T-Cell Responses After Allogeneic Stem Cell Transplantation By Pentamer and Streptamer Staining
Beloki L, Ciaurriz M, Ramirez N et al.
Key Points:
Investigated new modality for monitoring CMV-specific CD8+ T-cells (CTLs) by using pentamer (PM) and streptamer (ST) multimer complexes.
No CMV-specific CTLs detected.
Patients with CMV infection: rapid increase of CMV-specific-CTLs detected.
Implications:
- Using specific multimer-based might help distinguish patients at higher risk of recurrent virus reactivation.
View the original abstract on the ASH website.
