Profiles Of De Novo CD25-Positive Mature B-Cell Lymphomas
Fujiwara S, Tatara R, Okazuka K et al.




Key Points:
  • High expression level of CD25 correlated with poor prognosis following rituximab therapy.

  • Level of CD25 expression significantly higher in patients with MCL, CLL, MZL, and DLBCL compared to patients with reactive lymphadenopathy.

  • In CLL patients, the level of CD25 expression wide.

  • in patients with DLBCL the progression-free survival rate (PFS) after rituximab therapy inferior in patients with CD25+.

Implications:

  • Detection of CD 25 expression potential diagnostic and prognostic implications for BCL patients.

View the original abstract on the ASH website.






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