The Incidence and Risk Factors For Hematological Malignancies and Premalignant Hematological Disorders In HIV.
Jou E, Gligich O, Chan A et al.
Key Points:
Retrospective study explored database of HIV+ patients to assess incidence of different HM and premalignant disorders (PMD) in HIV+ patients.
Median duration of follow up in this study 60 months. total of 10,293 patients with a positive HIV test.
2.5% of patients diagnosed with HM or PMD.
80.6% of patients diagnosed with high grade lymphomas with DLBCL most frequent.
Implications:
- In HIV-related HM, male gender and discrete paraproteins likely risk factors but not oligoclonal or multiple paraproteins.
View the original abstract on the ASH website.
