Effectiveness Of Biosimilar Epoetin Alfa For The Treatment Of Chemotherapy-Induced Anemia In Patients With Hematological Malignancies
Agrawal1 SG, Guy A, O'Flaherty P et al.




Key Points:
  • Biosimilar Epoetin alfa effective, less costly and approved in Europe.

  • This pilot study performed to evaluate efficacy of biosimilar epoetin alfa (Sandoz, Germany) for management of chemotherapy-induced anemia in patients with hematological malignancies.

  • Out of nineteen patients analyzed (9 with CLL, 7 with myeloma, 3 with lymphoma), 12 had major response (increase of >2gm/dl) and 6 with minor response (increase of 1-2gm/dl).

  • Four patients transfusion-dependent at baseline, 3 of whom became transfusion-independent on biosimilar epoetin therapy.

Implications:

  • Biosimilar epoetin alfa effective for treatment of chemotherapy-induced anemia in patients with hematological malignancies.

View the original abstract on the ASH website.






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