Novel immunotherapeutic drugs show promising results.
An unmet need for accurate and specific biomarkers.
FLOCK identifies clusters of putatively similar cells in individual sample by multidimensional clustering of fluorescence marker and light-scattering measurements.
Identified common “cell signatures” across multiple patients.
Cell signatures then mapped back onto individual patient samples.
Analysis revealed distinct differences between controls and CLL patients.
Able to differentiate between distinct clinical subpopulations of patients.
Marker for overall health/disease status, and could be used for diagnosis, prognosis, and selection of optimal treatment.
This tool will be crucial for defining individual patient prognosis, and defining accurately matched treatment plan.
View the original abstract on the ASH website.
