Proposal For a Novel Scoring System For The Diagnosis Of CLL
Köhnke T, Wittmann V, Sauter D, et al.




Key Points:
  • Study investigators aimed to improve current modified Matutes score by including highly informative markers less informative and error-prone marker.

  • Modified Matutes score calculated from peripheral blood or bone marrow aspirates of patients with suspected B-cell lymphoproliferative disorders.

  • Patient cohorts: exploratory and validation cohort.

  • Sensitivity 97.1% for new score versus 98.6% for Matutes score.

Implications:

  • New scoring system for diagnosing CLL showed high sensitivity with markedly improved specificity compared to modified Matutes score.

View the original abstract on the ASH website.






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