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Found 15757 articles
Clinical implementation of MRI-based organs-at-risk auto-segmentation with convolutional networks for prostate radiotherapy
High conformality for OARs delineation achieved with two in-house trained networks.
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05/11/20
Investigation of the adolescent female breast transcriptome and the impact of obesity
There were 120 differentially expressed genes (DEG) in overweight/obese samples.
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05/11/20
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
Hyperphosphorylation of Ack1 and subsequent activation of antiapoptotic signaling via =AKT pathway contributed to ASK120067 resistance.
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05/13/20
Frequency and spectrum of PIK3CA somatic mutations in breast cancer
PIK3CA mutations in BC are heterogenous.
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05/13/20
Biological effects of selective COX-2 inhibitor NS398 on human glioblastoma cell lines
Comparable effects exerted by the COX-2 inhibitor NS398 on both GBM cell lines.
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05/13/20
Tumour-infiltrating lymphocytes and response to neoadjuvant letrozole in patients with early oestrogen receptor-positive breast cancer: analysis from a nationwide phase II DBCG trial
Increase in TILs significantly associated with pathological response.
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05/14/20
Novel methods for in vitro modeling of pancreatic cancer reveal important aspects for successful primary cell culture
Protocols for two- and three-dimensional PDAC primary cell cultures could successfully be established.
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05/13/20
Combined endocrine approaches vs endocrine therapy alone as first line treatment in elderly patients with hormone receptor-positive, HER2 negative, advanced breast cancer: to prescribe for the patient or the physician? A meta-analysis of phase II and III randomized clinical trials
Meta-analysis showed PFS advantage for experimental arms.
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05/13/20
Intraoperative radiotherapy with low energy x-rays for primary and recurrent soft-tissue sarcomas
Electronic IORT with low-energy photons safe treatment option for STS.
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05/14/20
CDX2 expression and perioperative patient serum affects the adhesion properties of cultured colon cancer cells
Adhesion abilities in pre- and postoperative serum resembled those of LS174T wild type cell line.
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05/14/20
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