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Found 15757 articles
Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation
LAT1 required for VEGF-A-dependent migration, invasion, tube formation.
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11/30/20
Targeting the myeloid checkpoint receptor SIRPα potentiates innate and adaptive immune responses to promote anti-tumor activity
SIRPα blockade with hAB21 promoted macrophage-mediated antibody-dependent phagocytosis of tumor cells.
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11/30/20
Navitoclax enhances the effectiveness of EGFR-targeted antibody-drug conjugates in PDX models of EGFR-expressing triple-negative breast cancer
Treatment with navitoclax plus ABT-414 caused significant reduction in tumor growth.
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11/30/20
A prospective follow-up study of the relationship between high-sensitivity C-reactive protein and primary liver cancer
Significant association of higher levels of hs-CRP with new-onset PLC.
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11/30/20
Clinicopathological features and recurrence patterns of combined hepatocellular-cholangiocarcinoma
Liver was most common recurrence site.
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12/04/20
Telomere lengths in women treated for breast cancer show associations with chemotherapy, pain symptoms, and cognitive domain measures: a longitudinal study
Race and age significantly associated with telomere length.
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12/04/20
A single-arm, phase 2 study of adjuvant chemotherapy with oral tegafur-uracil for pathologically lymphovascular invasion positive stage IA non-small cell lung cancer: LOGIK0602 study
2-year course of oral tegafur-uracil administration feasible.
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12/04/20
Radotinib enhances cytarabine (Ara-C)-induced acute myeloid leukemia cell death
Combination of radotinib and Ara-C found to induce AML cell apoptosis.
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12/04/20
Safety and clinical efficacy of BCMA CAR-T-cell therapy in multiple myeloma
Median progression-free survival (PFS) 12.2 months.
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12/03/20
Intestinal region-specific Wnt signalling profiles reveal interrelation between cell identity and oncogenic pathway activity in cancer development
Downregulation of location specific genes and differentiation markers in reaction to Wnt activation.
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12/03/20
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