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Patients reported lower levels of disease-related life interference and treatment burden. »
07/29/21
 
 
CDH1 germline variants have been linked to heritability in diffuse gastric (DGC) and lobular breast cancer (LBC). Studies have not yet assessed whether CDH1 is a cancer-susceptibility gene in other cancers. Herein, we mapped the landscape of pathogenic and likely pathogenic (P/LP) germline variants in CDH1 across various cancers and ethnicities. »
09/08/21
 
 
Patients who had at least partial response had significantly better overall and disease-free survival. »
10/27/20
 
Pathogenic and likely pathogenic variant load significantly increased in genes involved in cilia biogenesis »
03/12/21
 
Successful adoption of preemptive PGx-guided will require multifaceted effort to demonstrate clinical effectiveness. »
01/08/22


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