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Found 15757 articles
Anti-tumor treatment and healthcare consumption near death in the era of novel treatment options for patients with melanoma brain metastases
Patients receiving systemic treatment more likely to visit emergency room.
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03/05/22
INHBA is a mediator of aggressive tumor behavior in HER2+ basal breast cancer
Patients with HER2+ breast cancer and high levels of INHBA expression had worse outcomes.
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03/05/22
De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK+ ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells
WNT signaling cell surface receptor ROR2 represented robust and genuine marker of all ALK+ ALCL patient tumor samples.
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03/04/22
An update on radiomics techniques in primary liver cancers
Radiomics could support cancer detection, diagnosis, evaluation of prognosis.
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03/04/22
HDAC class I inhibitor domatinostat sensitizes pancreatic cancer to chemotherapy by targeting cancer stem cell compartment via FOXM1 modulation
Correlation of FOXM1 expression with poor progression free survival in PDAC chemotherapy-treated patients.
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03/03/22
Pan-cancer analysis identifies LMNB1 as a target to redress Th1/Th2 imbalance and enhance PARP inhibitor response in human cancers
LMNB1 level positively correlated with CD4+ Th2 cell infiltration and DNA homologous recombination repair.
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03/03/22
Primary central nervous system lymphoma high incidence and poor survival in Finnish population-based analysis
Age-adjusted relative survival rate 33% and corresponding 5-year survival rate 26%.
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03/03/22
Characterization of distinct circular RNA signatures in solid tumors
circLIFR experimentally validated to be downregulated in six solid tumors.
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03/02/22
Partial p53 reactivation is sufficient to induce cancer regression
p53 variant E177R induces immune cell infiltration and triggers cancer regression in vivo.
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03/02/22
Exposure-response analyses of cabozantinib in patients with metastatic renal cell cancer
Longer PFS observed for patients with dose reduction.
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03/02/22
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