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Found 15757 articles
Activity and resistance of a brain-permeable paradox breaker BRAF inhibitor in melanoma brain metastasis.
BRAF kinase domain duplication identified as frequently occurring driver of resistance to C1a.
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05/13/22
Chromatin Rewiring by Mismatch Repair Protein MSH2 Alters Cell Adhesion Pathways and Sensitivity to BET Inhibition in Gastric Cancer.
Role for MSH2 in GC epigenomic regulation and identify BET inhibition as potential therapy.
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05/09/22
Natural products as a means of overcoming cisplatin chemoresistance in bladder cancer.
Compounds can activate diverse array of different pathways.
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08/21/20
Increased expression of Profilin potentiates chemotherapeutic agent-mediated tumour regression.
ATRA binds with RAR/RXR to increase profilin expression.
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07/06/21
Quantifying the reduction of respiratory motion by mechanical ventilation with MRI for radiotherapy
RB significantly reduced respiratory motion amplitude by 39%.
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05/21/22
KMT2B promotes the growth of renal cell carcinoma via upregulation of SNHG12 expression and promotion of CEP55 transcription
SNHG12 highly expressed in RCC tissues and cells.
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05/21/22
Volasertib as a monotherapy or in combination with azacitidine in patients with myelodysplastic syndrome, chronic myelomonocytic leukemia, or acute myeloid leukemia: summary of three phase I studies
All dose-limiting toxicities grade 4 thrombocytopenia.
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05/21/22
Development and technical validation of an ultrasound nebulizer to deliver intraperitoneal pressurized aerosols in a rat colon cancer peritoneal metastases model
FDG-PET more sensitive to detect smaller PM nodules.
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05/21/22
Validation of genomic and transcriptomic models of homologous recombination deficiency in a real-world pan-cancer cohort
HRD-RNA model predictive of BRCA status in prostate, pancreatic, and non-small cell lung cancer.
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05/28/22
Experiences of resuming life after immunotherapy and associated survivorship care needs: a qualitative study among patients with metastatic melanoma.
Patients indicated they needed to find new balance which included learning to cope with uncertainty.
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05/21/22
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