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Found 15757 articles
A text-mining approach to study the real-world effectiveness and potentially fatal immune-related adverse events of PD-1 and PD-L1 inhibitors in older patients with stage III/IV non-small cell lung cancer
Safety analysis demonstrated higher incidence of pneumonitis among patients aged 65–74.
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03/14/23
MUC16 promotes triple-negative breast cancer lung metastasis by modulating RNA-binding protein ELAVL1/HUR
MUC16 highly expressed in TNBC and correlated with its target HuR.
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03/14/23
Distribution and prognostic impact of EGFR and KRAS mutations according to histological subtype and tumor invasion status in pTis-3N0M0 lung adenocarcinoma
EGFR mutation more likely to be harbored in female, never-smoker.
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03/14/23
Real-life use of trametinib after immunotherapy failure in BRAF wild-type advanced melanoma.
Trametinib may benefit some metastatic melanoma that progressed after chemotherapy.
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03/15/23
Dynamic assessment of serum chromogranin A and treatment response with abiraterone acetate in metastatic castration-resistant prostate cancer.
Increase in chromogranin associated with lower risk of treatment failure.
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12/10/22
Fragment length profiles of cancer mutations enhance detection of circulating tumor DNA in patients with early-stage hepatocellular carcinoma
Study provides rationale for subsequent clinical evaluation.
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03/13/23
A diagnostic circulating miRNA signature as orchestrator of cell invasion via TKS4/TKS5/EFHD2 modulation in human gliomas
Glioma datasets showed consistent deregulation of signature according to IDH mutation status.
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03/17/23
Tumor cell integrin beta 4 and tumor stroma E-/P-selectin cooperatively regulate tumor growth in vivo
Robust synergism between ITGB4 and E-/P-selectin for regulation of tumor growth.
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03/17/23
Changes in calpain-2 expression during glioblastoma progression predisposes tumor cells to temozolomide resistance by minimizing DNA damage and p53-dependent apoptosis
Calcium-dependent calpain proteases, in particular calpain-2, more abundant in glioblastoma.
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03/17/23
Novel Postoperative Serum Biomarkers in Atypical Meningiomas: A Multicenter Study.
Tumor size >5 cm, subtotal resection, and postoperative aspartate aminotransferase/alanine transaminase ratio >2 associated with higher P/R rates.
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09/30/22
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