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Found 15770 articles
The epigenetic evolution of glioma is determined by the IDH1 mutation status and treatment regimen.
Initial cell composition of tumor microenvironment varied between IDHwt and IDHmut tumors.
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12/13/23
A heterodimer of alpha beta hemoglobin chains functions as an innate anticancer agent.
Dimer downregulates expression of BRD4, GAB2, and IRS2 proteins.
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07/25/23
Tumor volumes in T3 supraglottic cancers treated with radiotherapy in the modern era: A study of the Canadian Head & Neck Collaborative Research Initiative.
Increasing primary tumor volume associated with worse OS and DFS.
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10/02/23
Preoperative and pre-chemotherapy CA-125 levels in high-risk early-stage ovarian cancer - An NRG/GOG study.
Elevated pre-chemotherapy CA-125 independently predicted worse recurrence-free survival.
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10/27/23
Addition of polygenic risk score to a risk calculator for prediction of breast cancer in US Black women
Combined model represents step forward for personalized breast cancer preventive care.
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01/02/24
Combined PDE4+MEK inhibition shows antiproliferative effects in NRASQ61 mutated melanoma preclinical models.
Significant ex vivo inhibition of proliferation with combination of roflumilast+cobimetinib observed.
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12/23/23
ABCB1 overexpression through locus amplification represents an actionable target to combat paclitaxel resistance in pancreatic cancer cells
ABCB1 expression associated with trend towards shorter survival.
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01/02/24
Caloric restriction and metformin selectively improved LKB1-mutated NSCLC tumor response to chemo- and chemo-immunotherapy
Metformin and CR do enhance response to chemo and chemo-immunotherapy.
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01/02/24
Development and Optimization of a Subtraction-Normalized Immunocyte Profiling Signature for Prostate Cancer Active Surveillance Risk Stratification.
Best final model for AS setting -- combining an immunocyte transcriptomic profile with prostate-specific antigen.
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12/26/23
Application of an artificial intelligence-based system in the diagnosis of breast ultrasound images obtained using a smartphone
AI showed 100% sensitivity and 75% specificity for malignant lesions.
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01/02/24
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