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Found 15815 articles
High mid-treatment tumour RNA disruption in patients with HER2-negative breast cancer is associated with improved disease-free survival after neoadjuvant chemotherapy
High tumour RNA disruption during neoadjuvant chemotherapy associated with improved DFS.
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08/11/25
Histone lactylation-boosted AURKB facilitates colorectal cancer progression by inhibiting HNRNPM-mediated PSAT1 mRNA degradation
AURKB bound to HNRNPM and interfered with its interaction with PSAT1 mRNA.
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08/11/25
A stacking ensemble framework integrating radiomics and deep learning for prognostic prediction in head and neck cancer
Model using combined PET and CT radiomics features achieved superior performance.
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08/13/25
MiR-7 inhibits progression of glioblastoma by impairing autophagy resolution, energy metabolism and ECM remodeling
Novel dual role of miR-7 regulating metabolism through impairment of mitochondrial function.
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08/14/25
Arginine depletion potentiates standard-of-care chemo-immunotherapy in preclinical models of high-risk neuroblastoma
Arginase BCT-100 profoundly disrupts neuroblastoma growth.
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08/14/25
CBCT-based online adaptive radiotherapy of the bladder -- geometrical and dosimetrical considerations compared to conventional IGRT
Treatment times approximately 1.5 times longer than IGRT.
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08/14/25
Exploring the mutational spectrum of key kinase genes PIK3CA, BRAF, EGFR, ALK and ROS1 in oral squamous cell carcinoma
Potential mutations on ROS1 identified that can have potential biomarker applications.
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08/18/25
Precise stratification of prognosis in pancreatic ductal adenocarcinoma patients based on pre- and postoperative genomic information
Postoperative factors significantly associated with shorter overall survival include low GATA6 expression and elevated CA19-9 level.
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08/18/25
CAFs exosomal miR-21-5p suppresses ferroptosis and promotes proliferation and migration in osteosarcoma
Capacity of CAFs-derived exosomal miR-21-5p to promote tumor growth and weight.
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08/19/25
JNK pathway suppression mediates insensitivity to combination endocrine therapy and CDK4/6 inhibition in ER+ breast cancer
Suppression of JNK signalling enables persistent growth during combined endocrine therapy and CDK4/6 inhibition.
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08/19/25
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