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Found 16137 articles
Circulating extracellular vesicles from early-stage lung cancer patients trigger endothelial activation to drive pre-metastatic niche formation through synergistic miR-29a and C4A signaling
miR-29a and C4A act synergistically through SPARC down-modulation promoting cancer cell colonization.
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05/13/26
Adjuvant stereotactic pancreatic radiotherapy (SPARTA trial): interim safety analysis of an ongoing phase II single center prospective study
Adjuvant SBRT in PC associated with acceptable tolerability.
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05/13/26
Full BLOOD count TRends for colorectal cAnCer deteCtion (BLOODTRACC): external validation of dynamic clinical prediction models for early detection of colorectal cancer in primary care
Under-predicted risk in those aged 70 + years, White individuals, and those with higher IMD.
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05/14/26
De-escalation of chemotherapy in HER2-positive breast cancer management: a systematic review and meta-analysis
Chemotherapy de-escalation may reduce severe toxicity in selected patients.
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05/14/26
Full BLOOD count TRends for colorectal cAnCer deteCtion (BLOODTRACC): external validation of dynamic clinical prediction models for early detection of colorectal cancer in primary care
Utilising temporal changes in FBC test could enhance risk stratification.
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05/14/26
Comparison of laparoscopic versus open approach surgery for gastric gastrointestinal stromal tumors in unfavorable surgical locations
L group exhibited significantly shorter and lower postoperative hospital stay.
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05/14/26
Bi-directional regulation between NAD/NAMPT and IFN-γ/PD-L1 axes via BRD4/IRF1 and mitochondrial respiration in metastatic cutaneous melanoma
NAMPT activity required to sustain IFN-γ signaling.
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05/14/26
Reliability and oncological safety of pedicled skin island therapeutic mammoplasty as an alternative to Grisotti mastopexy for centrally located breast cancer patients
No instances of positive margins, local recurrence, or distant metastasis.
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05/14/26
Co-targeting CDK4/6 and MEK reverses mesenchymal transition in therapy-refractory BRAF-altered pediatric high-grade glioma
Tumors particularly vulnerable to combined abemaciclib and trametinib treatment.
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05/16/26
Tie2 inhibition disrupts TMEM doorway function and reduces dissemination in pancreatic ductal adenocarcinoma
TMEM doorways detectable in human PDAC tissues.
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05/16/26
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