The Vimentin gene plays a pivotal role in epithelial-to-mesenchymal transition and is known to be overexpressed in the prognostically poor basal-like breast cancer subtype. »
12/13/12

Curcum may have a protective role during the process of bladder carcinogenesis by inhibiting the NF-κB pathway and its downstream products. »
12/19/12

Resveratrol shows chemopreventive activity in a variety of human cancers by targeting mitochondria and triggering apoptosis. The purpose of this study was to investigate the antitumor action of resveratrol in bladder cancer and its underlying mechanism. »
12/21/12

Information on human papillomavirus (HPV) type distribution is necessary to evaluate the potential impact of current and future HPV vaccines. We estimated the relative contribution (RC) to invasive cervical cancer (ICC) and precancerous cervical lesions of the nine HPV types (HPV 6/11/16/18/31/33/45/52/58) included in an HPV vaccine currently under development. »
12/29/12

G-protein-coupled estrogen receptor (GPER/GPR30) was reported to bind 17beta-estradiol (E2), tamoxifen, and ICI 182,780 (fulvestrant) and promotes activation of epidermal growth factor receptor (EGFR)-mediated signaling in breast, endometrial and thyroid cancer cells. Although lung adenocarcinomas express estrogen receptors alpha and beta (ERalpha and ERbeta), the expression of GPER in lung cancer has not been investigated. The purpose of this study was to examine the expression of GPER in lung cancer. »
12/28/12

History of PIN is highly predictive of prostate cancer in African-Americans. »
12/24/12

Vitamin D exposure is a possible modifiable risk factor of ovarian cancer among African Americans. »
10/31/12

Mutation of E3 ligase motif dramatically reduces the metastasis suppressor function of BRMS1. »
12/28/12

shRNA targeting ATX inhibited the growth of human gastric cancer xenografts in nude mice. »
12/25/12

EFNA1 expression is a useful marker for predicting high risk of relapse and cancer-related death in CRC patients »
12/23/12