Abnormal activation of the Wnt/β-catenin signaling pathway is common in human cancers, including cervical cancer. Many papers have shown that SRY (sex-determining region Y)-box (SOX) family genes serve as either tumor suppressor genes (TSGs) or oncogenes by regulating the Wnt signaling pathway in different cancers. We have demonstrated recently that epigenetic silencing of SOX1 gene occurs frequently in cervical cancer. However, the possible role of SOX1 in cervical cancer remains unclear. This study aimed to explore whether SOX1 functions as a TSG in cervical cancer. »
05/07/13

Combined detections of B7-H3 and MMP2 protein expression could identify patients at high risk in disease recurrence and prognosis more efficiently. »
08/16/13

Lipegfilgrastim 6 mg is as effective as pegfilgrastim in reducing neutropenia »
08/14/13

Computer-derived syringic acid derivatives possess selective anti-mitogenic activity on human malignant melanoma cells »
08/19/13

High renal cancer selectivity of EA combined with its ability to induce multiple mechanisms of cell death »
08/20/13

Molecular fingerprinting seems to be able to better sub-classify morphologically heterogeneous tumours »
08/15/13

Chemokine receptor CXCR4 crucial for maintaining the self-renewal, proliferation, therapeutic resistance of GSCs. »
08/21/13

All five Hodgkin lymphoma cell lines exhibited chromosome instability »
08/20/13

Reversion of PRKD1 promoter methylation with inhibitor decitabine blocks tumor spread »
08/23/13

PR expression is not associated with prognosis in ER-negative breast cancer »
08/23/13