microRNA 21 (miR-21) has been demonstrated to be significantly elevated in many types of cancers, including the hepatocellular carcinoma (HCC). In the present study, we investigated the role of miR-21 in HCC by identifying its novel targets, as well as its underlying molecular mechanism. »
10/10/13

Contribution of stromal Hedgehog (Hh) signaling is evident in the prostate gland in mice, but needs translation to human tissues if Hh therapeutics are to be used effectively. Our goal was to determine if primary human prostate fibroblasts contain cilia, and respond to prostate Hh signaling. »
02/11/13

AA improves OS and is well tolerated in both elderly patients and younger patients with mCRPC following docetaxel. »
06/20/13

Sigma-2 ligands are a promising tumour-targeting drug delivery agent. »
09/05/13

This phase III trial was performed to assess the potential benefit of adding maintenance erlotinib to bevacizumab after a first-line chemotherapy regimen with bevacizumab for advanced non-small-cell lung cancer (NSCLC). »
10/09/13

Polymorphisms also appear to be associated with gastric cancer progression. »
08/02/13

Serum miR-106b and miR-21 may provide a novel and stable marker of increased risk for early gastric cancer. »
05/31/13

Therapeutic potential of silencing DcR3 expression by RNAi in colon cancer. »
08/05/13

Patients with colorectal cancer who have diabetes mellitus are at greater risk for all-cause and cancer-specific mortality. »
10/10/13

nsPEFs is able to inhibit human breast cancer development and suppress tumor blood vessel growth. »
05/25/13