The purpose of this study was to identify the DNA methylation status of the mitogen-activated protein kinase (MAPK) signal-inhibiting genes dual-specificity phosphatase 4 (DUSP4) and 6 (DUSP6); and serpin peptidase inhibitor A member 5 (SERPINA5) in thyroid cancer. »
11/14/13

Promoter hypermethylation of RRAD is a frequent, tissue-specific event in ESCC. »
11/14/13

Resected GAC exhibited differential expression of TS and ERCC1. »
02/26/13

Colitis and progression to cancer are dependent on stromal PI3K and sensitive to treatment with LY294002. »
03/13/13

PSK reduced the expression of MMP2 and MMP9 mRNAs. »
11/14/13

eIF5A regulon can be modulated by drugs such as ciclopirox or deferiprone which might be repositioned to control cancer cell growth. »
11/14/13

Urothelial bladder cancer is the ninth most common cancer. Despite surgical and chemotherapeutic treatment the prognosis is still poor once bladder cancer progresses to a muscle-invasive state. Discovery of new diagnostic markers and pathophysiologic effectors might help to contribute to novel diagnostic and therapeutic options. The extracellular matrix microenvironment shaped by the extracellular matrix critically affects tumor cell and stroma cell functions. Therefore, aim of the present study was to assess the possible implication of the small leucine-rich proteoglycan biglycan in progression of human urothelial bladder cancer. »
11/14/13

Low molecular weight chitosan delivery system has the capacity to transport large amounts of siRNA across the urothelium »
11/14/13

The use, effectiveness, and tolerability of tamoxifen, aromatase inhibitors, and trastuzumab in early and advanced male breast cancer were examined at a population level. »
03/31/13

Polymorphisms in miRNAs identified to incur increased risk of breast cancer »
11/07/13