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Found 15790 articles
Therapeutic effects of lentivirus-mediated shRNA targeting of cyclin D1 in human gastric cancer
Tumor growth of the lentivirus-treated group was significantly inhibited compared to growth of the control group.
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03/11/14
Early diagnostic value of Survivin and its alternative splice variants in breast cancer
Survivin-2B may serve as a diagnostic prognostic marker, a "liquid biopsy," in early breast cancer.
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03/12/14
Zoledronic acid inhibits pulmonary metastasis dissemination in a preclinical model of Ewing's sarcoma via inhibition of cell migration
ZA could be used early in the treatment of ES to inhibit bone tumor growth but also to prevent the early metastatic events to the lungs.
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03/10/14
Plasma 25-hydroxyvitamin D3 is associated with decreased risk of postmenopausal breast cancer in whites: a nested case-control study in the multiethnic cohort study
Circulating 25(OH)D3 and 25(OH)D associated with reduced risk of postmenopausal breast cancer among whites, but not in other ethnic groups.
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01/17/14
TAp63 suppress metastasis via miR-133b in colon cancer cells.
TAp63 expression is downregulated in colon cancer, and microRNA-133b is a transcriptional target of TAp63.
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09/26/13
HO-3867, a safe STAT3 inhibitor, is selectively cytotoxic to ovarian cancer.
DAP compound HO-3867 selectively inhibited STAT3 phosphorylation.
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03/05/14
5α-reductase type 3 enzyme in benign and malignant prostate.
Human prostate tissues contain a third 5α-reductase that was inhibited poorly by dutasteride.
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02/24/13
Cisplatin-induced epigenetic activation of miR-34a sensitizes bladder cancer cells to chemotherapy
Cisplatin-based chemotherapy induced demethylation of miR-34a promoter and increased miR-34a expression.
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01/15/14
Identification of a promising PI3K inhibitor for the treatment of multiple myeloma through the structural optimization
Suppression of BENC-511 on MM tumor growth was associated with decreased PI3K/AKT activity and increased cell apoptosis.
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01/15/14
A ROS/STAT3/HIF-1α signaling cascade mediates EGF-induced TWIST1 expression and prostate cancer cell invasion.
ROS/STAT3/HIF-1α/TWIST1/N-cadherin signaling cascade, providing novel biomarkers and promising therapeutic targets for prostate cancer cell progression.
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06/20/13
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