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Found 15790 articles

TRAIL-induced programmed necrosis as a novel approach to eliminate tumor cells

Ceramide as a key mediator of death receptor-induced programmed necrosis. »
02/07/14

Microvascular density of regenerative nodule to small hepatocellular carcinoma by automated analysis using CD105 and CD34 immunoexpression

CD34 antibody is a good endothelial marker for hepatic carcinogenesis. »
02/07/14

The novel arylindolylmaleimide PDA-66 displays pronounced antiproliferative effects in acute lymphoblastic leukemia cells

PDA-66 inhibited the proliferation of ALL cells significantly by reduction of metabolic activity. »
02/06/14

Multivariate and subgroup analyses of a randomized, multinational, phase 3 trial of decitabine vs treatment choice of supportive care or cytarabine in older patients with newly diagnosed acute myeloid leukemia and poor- or intermediate-risk cytogenetics

Response to decitabine in AML is associated with known prognostic factors related to both patient demographics and disease characteristics. »
02/06/14

Concerted down-regulation of immune-system related genes predicts metastasis in colorectal carcinoma

Metastasis could be well predicted by a set of gene expression markers consisting exclusively of genes related to the MHC class II complex. »
02/05/14

Examestane in advanced or recurrent endometrial carcinoma: a prospective phase II study by the Nordic Society of Gynecologic Oncology (NSGO)

Treatment of estrogen positive advanced or recurrent endometrial cancer with aromatase inhibitor resulted in a response rate of 10% and lack of progression after 6 months in 35% of the patients. »
02/05/14

The clinical value of the quantitative detection of four cancer-testis antigen genes in multiple myeloma

Cancer-testis antigen genes might ct as diagnostic and prognostic markers in MM. »
02/05/14

Sensitization of U937 leukemia cells to doxorubicin by the MG132 proteasome inhibitor induces an increase in apoptosis by suppressing NF-kappa B and mitochondrial membrane potential loss

MG132 sensitizes U937 leukemia cells to DOX-induced apoptosis, increasing its anti-leukemic effectiveness. »
02/04/14

Targeted Prostate Cancer Screening in BRCA1 and BRCA2 Mutation Carriers: Results from the Initial Screening Round of the IMPACT Study.

Germline genetic markers can be used to identify men at higher risk of prostate cancer. »
11/03/13

High GMFG expression correlates with poor prognosis and promotes cell migration and invasion in epithelial ovarian cancer.

GMFG expression independently predicts poorer prognosis in patients with EOC. »
10/17/13

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