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Found 15807 articles
RAC1b overexpression correlates with poor prognosis in KRAS/BRAF WT metastatic colorectal cancer patients treated with first-line FOLFOX/XELOX chemotherapy.
RAC1b expression as a predictor of chemotherapy efficacy in mCRC.
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07/21/13
MEK1/2 inhibitors in the treatment of gynecologic malignancies.
MEK inhibitors are small molecules that inhibit MEK phosphorylation.
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09/25/13
The dual PI3K/mTOR inhibitor PKI-587 enhances sensitivity to cetuximab in EGFR-resistant human head and neck cancer models.
Phosphoinositide 3-kinase/mammalian target of rapamycin inhibition has an important role in the rescue of cetuximab resistance.
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04/04/14
Prognostic significance of spontaneous antibody responses against tumor-associated antigens in malignant melanoma patients.
Multivariate analyses identified specific humoral immune responses as prognostic factors independently of age, chemotherapy and immunotherapy.
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11/19/13
A bispecific transmembrane antibody simultaneously targeting intra- and extracellular epitopes of the epidermal growth factor receptor inhibits receptor activation and tumor cell growth.
Novel type of membrane-anchored intrabodies in tumor cells and distinct modes of action of mono- and bispecific variants.
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09/15/13
Long non-coding RNA HOTAIR is a powerful predictor of metastasis and poor prognosis and is associated with epithelial-mesenchymal transition in colon cancer.
HOTAIR may also be a valuable predictor for colon cancer management.
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01/25/14
Src/caveolin-1-regulated EGFR activation antagonizes TRAIL-induced apoptosis in gastric cancer cells.
Src activates EGFR through the interaction of both Src-EGFR and Src-caveolin-1.
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03/06/14
Triage by methylation-marker testing versus cytology in women who test HPV-positive on self-collected cervicovaginal specimens (PROHTECT-3): a randomised controlled non-inferiority trial.
DNA methylation analysis of MAL and miR-124-2 genes on HPV-test-positive self-samples is non-inferior to cytology triage.
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02/13/14
MicroRNAs in Cervical Cancer: Evidences for a miRNA Profile Deregulated by HPV and Its Impact on Radio-Resistance.
Interaction between HR-HPV established infections and specific cellular miRNAs.
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02/16/14
Serum One-Carbon Metabolites and Risk of Cervical Cancer.
Reduced expression of hnRNP-E1 might be involved with the cervical cancer pathogenesis.
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05/23/14
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