HIF3alpha transcripts, expressing a 3'UTR containing the miR-485-5p and miR-210-3p target sites, are expressed in all sarcoma cell lines and upregulated upon hypoxia. »
06/13/14
14-3-3sigma is implicated in promoting tumor development of various malignancies. However, the clinical relevance of 14-3-3sigma in hepatocellular carcinoma (HCC) tumor progression and modulation and pathway elucidation remain unclear. »
06/12/14
Peroxisome proliferator-activated receptors gamma (PPARgamma) ligands have been shown to inhibit the growth of non-small cell lung cancer (NSCLC) cells. However, the mechanisms underlying this effect remain incompletely elucidated. »
06/13/14