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Found 15807 articles
Prognostic impact of MGMT promoter methylation and MGMT and CD133 expression in colorectal adenocarcinoma
MGMT expression may be an OS biomarker as useful as tumor stage or differentiation grade.
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07/11/14
Ubiquitin-conjugating enzyme complex Uev1A-Ubc13 promotes breast cancer metastasis through nuclear factor-[cyrillic small letter ka]B mediated matrix metalloproteinase-1 gene regulation
Overexpression of UEV1A alone, but not UEV1C or MMS2, is sufficient to induce cell invasion in vitro and metastasis in vivo.
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07/14/14
Peroxiredoxin-1 protects estrogen receptor alpha from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer
High PRDX1 protein expression is a biomarker of improved prognosis.
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07/10/14
Sequencing of breast cancer stem cell populations indicates a dynamic conversion between differentiation states in vivo
CSCs must be a population of cells that can dynamically switch from differentiated tumor cells, and vice versa.
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07/06/14
Nicotine-mediated invasion and migration of non-small cell lung carcinoma cells by modulating STMN3 and GSPT1 genes in an ID1-dependent manner
Overexpression of ID1 in two different cell lines induced STMN3 and GSPT1 at the transcriptional level.
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07/16/14
Influence of secreted frizzled receptor protein 1 (SFRP1) on neoadjuvant chemotherapy in triple negative breast cancer does not rely on WNT signaling
Knockdown of SFRP1 in triple negative breast cancer cells renders the cells more resistant to standard chemotherapy.
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07/17/14
LincRNAs MONC and MIR100HG act as oncogenes in acute megakaryoblastic leukemia
lncRNAs MONC and MIR100HG are highly expressed in AMKL blasts.
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07/15/14
Iodine-125 induces apoptosis via regulating p53, microvessel density, and vascular endothelial growth factor in colorectal cancer
I-125 protests against CRC via increasing the protein level of p53 and decreasing the level of vascular endothelial growth factor (VEGF).
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07/17/14
Histone deacetylase 8 is deregulated in urothelial cancer but not a target for efficient treatment
Efficient siRNA-mediated knockdown of HDAC8 reduced proliferation up to 45%.
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07/10/14
Wild-type and mutant p53 differentially regulate NADPH oxidase 4 in TGF-β-mediated migration of human lung and breast epithelial cells.
Kknockdown of endogenous mutant p53 (R280K) in TGF-β-treated MDA-MB-231 metastatic breast epithelial cells resulted in decreased Nox4 protein.
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01/20/14
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