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Found 15815 articles
Histone trimethylation at H3K4, H3K9 and H4K20 correlates with patient survival and tumor recurrence in early-stage colon cancer
Combined nuclear expression of histone modifications H3K4me3, H3K9me3 and H4K20me3 is prognostic in early-stage colon cancer.
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07/22/14
Hypoxia represses microRNA biogenesis proteins in breast cancer cells
Support for the existence of feedback mechanisms in the regulation of the microRNA biogenesis pathway.
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07/22/14
The influence of tamoxifen on normal mouse mammary gland homeostasis
No long lasting effects of tamoxifen on mammary repopulating unit numbers or on pubertal ductal development were observed.
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07/24/14
The RAC1 P29S Hotspot Mutation in Melanoma Confers Resistance to Pharmacological Inhibition of RAF.
RAC1 P29S status may offer a predictive biomarker for RAF inhibitor resistance.
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07/25/14
Clinical activity of enzalutamide versus docetaxel in men with castration-resistant prostate cancer progressing after abiraterone.
Treatment with either enzalutamide or docetaxel produced modest PSA responses and PFS intervals.
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05/19/14
Antiproliferative activity of novel imidazopyridine derivatives on castration-resistant human prostate cancer cells.
AMD and DME treatments inhibited both AR and PI3K/Akt signaling.
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05/18/14
E3 ubiquitin ligase HOIP attenuates apoptotic cell death induced by cisplatin.
HOIP-regulated antiapoptotic signaling pathway identified.
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03/31/14
Epigenetic Targeting of Ovarian Cancer Stem Cells.
Epigenome-targeting strategies have the potential to delay tumor progression by re-programming residual cancer stem-like cells.
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07/19/14
Polymorphisms of peroxisome proliferator-activated receptors and survival of lung cancer and upper aero-digestive tract cancers.
The variant homozygote CC (vs. TT) of PPARD rs3734254 was inversely associated with mortality.
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03/31/14
Does adjuvant radiotherapy benefit patients with diffuse-type gastric cancer? Results from the Surveillance, Epidemiology, and End Results database.
Lack of a long-term survival benefit for adjuvant chemoradiation therapy among patients with diffuse-type gastric cancer.
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03/17/14
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