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Found 15815 articles
Selenoprotein and antioxidant genes and the risk of high-grade prostate cancer and prostate cancer recurrence.
Suggestive evidence that genetic variation in selenoproteins and related antioxidant enzymes may be associated with risk of high-grade disease.
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05/01/14
INPP4B is highly expressed in prostate intermediate cells and its loss of expression in prostate carcinoma predicts for recurrence and poor long term survival.
INPP4B expression was reduced in prostate carcinoma.
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04/08/14
Galectin-3 inhibition suppresses drug resistance, motility, invasion and angiogenic potential in ovarian cancer.
Galectin-3C significantly reduces the growth, motility, invasion.
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02/20/14
Inhibition of mTORC1/2 overcomes resistance to MAPK pathway inhibitors mediated by PGC1α and Oxidative Phosphorylation in melanoma.
Findings highlight the significance of OxPhos in melanoma.
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10/10/14
Ramucirumab: Successfully Targeting Angiogenesis in Gastric Cancer.
RAINBOW trial confirmed the survival advantage of this antiangiogenic agent in gastric cancer.
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10/05/14
Smoking history predicts for increased risk of second primary lung cancer: A comprehensive analysis.
Increasing tobacco exposure is associated with a higher risk of SPLC.
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08/23/14
Efficacy of Anti-RON Antibody Zt/g4-Drug Maytansinoid Conjugation (Anti-RON ADC) as a Novel Therapeutics for Targeted Colorectal Cancer Therapy.
Zt/g4-DM1 is highly effective in targeted inhibition of CRC cell-derived tumor.
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10/09/14
Clinical validation of the HPV-risk assay, a novel real-time PCR assay for detection of high-risk human papillomavirus DNA by targeting the E7 region.
HPV-Risk assay showed clinical sensitivity for CIN2+ of 97.1%.
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01/03/14
Strong therapeutic potential of γ-secretase inhibitor MRK003 for CD44-high and CD133-low glioblastoma initiating cells.
MRK003 is partially mediated by the Akt pathway.
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05/13/14
P-REX1 creates a positive feedback loop to activate growth factor receptor, PI3K/AKT and MEK/ERK signaling in breast cancer.
P-REX1 expression was highest in estrogen receptor-positive breast tumors.
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06/07/14
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