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Found 15815 articles
Downregulation of Msi1 suppresses the growth of human colon cancer by targeting p21cip1.
Knockdown of Msi1 significantly suppressed the proliferation, colony formation and tumor sphere formation.
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09/07/14
Telomere length is a novel predictive biomarker of sensitivity to anti-EGFR therapy in metastatic colorectal cancer.
Those with longer TL had a superior median progression-free survival.
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09/26/14
Risk of leukaemia or cancer in the central nervous system among children living in an area with high indoor radon concentrations: results from a cohort study in Norway.
An elevated nonsignificant risk for cancer in the central nervous system was observed.
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04/16/14
Cholera toxin, a typical protein kinase A activator, induces G1 phase growth arrest in human bladder transitional cell carcinoma cells via inhibiting the c-Raf/MEK/ERK signaling pathway.
Effect due to PKA-dependent inactivation of the c-Raf/Mek/Erk pathway.
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09/10/13
Long noncoding RNA GHET1 promotes the development of bladder cancer.
Inhibition of GHET1 reversed the epithelial-mesenchymal-transition in bladder cancer cell line.
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11/15/14
The increasing roles of epigenetic in breast cancer: Implications for pathogenicity, biomarkers, prevention and treatment.
DNA Methyltransferase Inhibitors (DNMTi) and Histone Desacetylase Inhibitors (HDACi) have shown encouraging results in BC, THOUGH their action remains non-specific.
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08/27/14
Gain-of-function of mutant p53: mutant p53 enhances cancer progression by inhibiting KLF17 expression in invasive breast carcinoma cells.
Mutant-p53 plays a key role to suppress KLF17
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01/23/14
Shift in GATA3 functions, and GATA3 mutations, control progression and clinical presentation in breast cancer
Some GATA3 effects shift from tumor suppressing- to tumor promoting during tumorigenesis.
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11/20/14
Calmodulin antagonists induce cell cycle arrest and apoptosis in vitro and inhibit tumor growth in vivo in human multiple myeloma
Treatment with W-7 and W-13 resulted in the dose-dependent inhibition of cell proliferation in various MM cell lines.
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11/26/14
Hypoxia, blood flow and metabolism in squamous-cell carcinoma of the head and neck: correlations between multiple immunohistochemical parameters and PET
HIF-1alpha correlated with GLUT-1.
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11/24/14
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