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Found 15815 articles
Association of ERG and TMPRSS2-ERG with grade, stage, and prognosis of prostate cancer is dependent on their expression levels.
Decreased PTEN expression, alone and also combined with TMPRSS2-ERG or with ERG overexpression, was associated with GS ≥7 tumors.
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12/30/14
High-temperature-required protein A2 as a predictive marker for response to chemotherapy and prognosis in patients with high-grade serous ovarian cancers.
Negative HtrA2 expression was identified as an independent worse prognostic factor for progression-free survival.
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09/29/14
Paracrine effect of NRG1 and HGF drives resistance to MEK inhibitors in metastatic uveal melanoma.
Neuregulin 1 (NRG1) and hepatocyte growth factor (HGF) provide resistance to MEK inhibition.
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05/09/15
KRAS and BRAF mutations are prognostic biomarkers in patients undergoing lung metastasectomy of colorectal cancer.
In multivariate analysis, WT BRAF and WT KRAS had a significant impact on OS.
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05/09/14
Small molecules alter VEGFR and PTEN expression in HPV-positive and -negative SCC: new hope for targeted-therapy.
The tested drugs displayed a remarkable anti-angiogenic effect by inhibition of VEGFR1 and -2 expression.
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03/10/15
High expression of RELM-α correlates with poor prognosis and promotes angiogenesis in gastric cancer.
Silencing of RELM-α expression may regulate the proliferation, invasion and migration of gastric cancer cells by targeting VEGF/MMP-9.
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12/23/14
Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting cancer stem cells.
Inhibiting LGR5 glycosylation resulted in depleted surface expression and reduced localisation in the cis-Golgi network.
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10/10/14
Indoleamine-2,3-dioxygenase (IDO) metabolic activity is detrimental for cervical cancer patient survival.
High levels of kynurenine were further associated with parametrial invasion and tumor size.
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02/15/15
MiR-137 inhibits proliferation and angiogenesis of human glioblastoma cells by targeting EZH2.
EZH2 was identified as a direct target of miR-137.
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08/06/14
Novel anti IGFBP2 single chain variable fragment inhibits glioma cell migration and invasion.
In vitro inhibition of extracellular IGFBP2 activity by using human scFv results in significant reduction of glioma cell migration and invasion.
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10/11/14
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