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Found 15815 articles
Identification of novel drugs to target dormant micrometastases
Screening 13,000 compounds identified two leads with low toxicity in mice.
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05/14/15
Na/K-ATPase as a target for anticancer drugs: studies with perillyl alcohol
Involvement of JNK1/2 in programmed cell death.
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05/15/15
Niclosamide suppresses cell migration and invasion in enzalutamide resistant prostate cancer cells via Stat3-AR axis inhibition.
Niclosamide inhibited Stat3 phosphorylation and expression of downstream target genes.
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02/13/15
GAGE12 mediates human gastric carcinoma growth and metastasis.
GAGE12 overexpression augmented migration, tumor sphere formation and sustained in vivo tumor growth.
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10/06/14
Non-steroidal anti-inflammatory drugs and the risk of head and neck cancer: A case-control analysis.
Decreased risk for HNC associated with regular use of ibuprofen.
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01/19/15
Plasminogen activator inhibitor-1 regulates tumor initiating cell properties in head and neck cancers.
PAI-039 decreased the activity of the core promoter.
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11/17/14
Expression of Formyl-peptide Receptors in Human Lung Carcinoma.
FPR expression is lower in types of human lung cancer tissues.
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05/13/15
Hesperetin Induces the Apoptosis of Gastric Cancer Cells via Activating Mitochondrial Pathway by Increasing Reactive Oxygen Species.
Significantly inhibited (P < 0.05), and dose- and time-dependent effectse observed.
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01/05/15
Ginkgo biloba extract enhances chemotherapy sensitivity and reverses chemoresistance through suppression of the KSR1-mediated ERK1/2 pathway in gastric cancer cells.
EGb 761 enhanced the chemotherapy sensitivity and reversed the chemoresistance.
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01/09/15
FOXM1-mediated downregulation of uPA and MMP9 by 3,3'-diindolylmethane inhibits migration and invasion of human colorectal cancer cells.
DIM significantly reduced the mRNA and protein levels of FOXM1 in the DLD-1 and HCT116 cells.
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02/27/15
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