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Found 15815 articles
Src Inhibition Blocks c-Myc Translation and Glucose Metabolism to Prevent the Development of Breast Cancer.
Src kinase blockade with the small molecule inhibitor saracatinib prevented the disorganized 3D growth of ER- mammary epithelial cells.
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09/19/15
Epigenomic profiling of DNA methylation in paired prostate cancer versus adjacent benign tissue.
DNA methylation profiles accurately distinguished between PCa and benign tissue samples.
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06/15/15
CD73 is associated with poor prognosis in high-grade serous ovarian cancer.
CD73 as a prognostic marker of patient survival.
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09/13/15
Distinct profiles for mitochondrial t-RNAs and small nucleolar RNAs in locally invasive and metastatic colorectal cancer.
MT-TF (phenylalanine) and snord12B expression correlated with a substantial number of miRNAs and mRNAs.
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09/20/15
NF-κB-dependent and -independent epigenetic modulation using the novel anti-cancer agent DMAPT.
Lower H3K36me3 possible epigenetic marker of constitutive NF-κB activity.
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05/30/14
The correlation between HLA-DRB1 and HLA-DQB1 gene polymorphisms and cytokines in HPV16 infected women with advanced cervical cancer.
Eight HLA-DRB1 alleles and four HLA-DQB1 alleles were found.
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09/20/15
Transforming growth factor-β signaling induced during prostate cancer cell death and neuroendocrine differentiation is mediated by bone marrow stromal cells.
Treatment of castration-resistant prostate cancer cells with SB-431542 resulted in significant reduction of apoptosis mediated by HS-5 BMSCs.
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05/11/15
Expression and prognostic significance of microRNA-451 in human epithelial ovarian cancer.
MiR-451 expression was significantly downregulated in EOC compared with normal ovarian tissues.
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09/23/15
BRAF inhibitor rechallenge in patients with advanced BRAF V600-mutant melanoma.
Intermittent treatment with BRAF inhibitors could provide clinical benefit.
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09/24/15
R331W Missense Mutation of Oncogene YAP1 Is a Germline Risk Allele for Lung Adenocarcinoma With Medical Actionability.
YAP1 mutation was shown to increase the colony formation ability and invasion potential of lung cancer cells.
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06/08/15
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