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Found 15815 articles
Transformation of enriched mammary cell populations with polyomavirus middle T antigen influences tumor subtype and metastatic potential
Tumors arising from the luminal CD133−, basal, and stem cell populations were highly metastatic.
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10/01/15
Long-term primary culture of a clear cell ovarian carcinoma reveals an epithelial–mesenchymal cooperative interaction
Epithelial not mesenchymal cells undergo DNA replication.
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09/24/15
Burkitt lymphoma beyond MYC translocation: N-MYC and DNA methyltransferases dysregulation
Alternative way for the activation of lymphomagenesis in these cases, based on global changes in methylation landscape.
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10/09/15
GSK-3β controls autophagy by modulating LKB1-AMPK pathway in prostate cancer cells.
Inhibition of GSK-3β activity resulted in a significant decline of cellular ATP production.
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09/08/15
Mutant p53 expression in fallopian tube epithelium drives cell migration.
Combining p53(R273H) with KRAS(G12V) activation caused transformation of MOE into high-grade sarcomatoid carcinoma.
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10/24/14
Angiopoietin-2 is a negative prognostic marker in small cell lung cancer.
Angiopoietin-2 (sAngiopoietin-2) associated with a worse overall survival and remained independently associated with survival in the multivariate analysis (p=0.008).
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07/28/15
MiRNA Expression Analysis of Pretreatment Biopsies Predicts the Pathological Response of Esophageal Squamous Cell Carcinomas to Neoadjuvant Chemoradiotherapy.
Combined qPCR of the 4 miRNAs provides the possibility of ESCC neo-CRT response prediction.
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10/08/15
Loss of FOXO1 promotes gastric tumour growth and metastasis through upregulation of human epidermal growth factor receptor 2/neu expression.
HER2 expression is critical to the induction of GC cell metastasis.
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05/04/15
Overexpression of PGC‑1α enhances cell proliferation and tumorigenesis of HEK293 cells through the upregulation of Sp1 and Acyl-CoA binding protein.
Increased Sp1 expression might contribute to enhanced ACBP expression by PGC‑1α.
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11/10/14
Upregulation of miR-20a and miR-10a expression levels act as potential biomarkers of aggressive progression and poor prognosis in cervical cancer.
Cervical cancer patients with high expression of miR-10 have shorter overall survival than patients with low expression.
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08/17/15
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