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Found 15815 articles
Demethylation of HIN-1 reverses paclitaxel-resistance of ovarian clear cell carcinoma through the AKT-mTOR signaling pathway
Expressions of phospho-AKT at Ser473 and Thr308 and phospho-mTOR decreased in the OCCC cells with a high expression of HIN-1.
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10/24/15
Celastrol induces cell cycle arrest by MicroRNA-21-mTOR-mediated inhibition p27 protein degradation in gastric cancer
miR-21 overexpression restored the decrease of mTOR activity.
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10/24/15
Hypoxia biomarkers in squamous cell carcinoma of the uterine cervix
Expression of HIF-1α or CAIX did not correlate with the fraction of hypoxic tissue in any of the two tumor lines.
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10/26/15
Exosomes derived from miR-122-modified adipose tissue-derived MSCs increase chemosensitivity of hepatocellular carcinoma
miR-122-transfected AMSC can effectively package miR-122 into secreted exosomes.
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10/29/15
Tissue thioredoxin reductase-1 expression in astrocytomas of different grades.
Expression of TrxR1, as assessed by both qRT-PCR and immunostaining, correlated highly with both the astrocytoma grade and Ki-67 index.
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06/17/14
Saracatinib as a metastasis inhibitor in metastatic castration-resistant prostate cancer: A University of Chicago Phase 2 Consortium and DOD/PCF Prostate Cancer Clinical Trials Consortium Study.
Only 26% of patients had stable disease after 8 weeks and thus proceeded to randomization.
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06/23/15
Interleukin-6 Stimulates Defective Angiogenesis.
Implications for the use of cancer therapies that target VEGF or IL6.
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05/11/15
Altered purinergic signaling in the tumor associated immunologic microenvironment in metastasized non-small-cell lung cancer.
Data suggest a role for CD39 in lung cancer tumor microenvironment.
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08/05/15
Tumor genotype determines phenotype and disease-related outcomes in thyroid cancer: a study of 1510 patients.
The prognostic significance of molecular signature in thyroid cancer (TC) is undefined but can potentially change surgical management.
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08/11/15
Impact of KITENIN on tumor angiogenesis and lymphangiogenesis in colorectal cancer.
KITENIN promotes tumor progression by enhancing angiogenesis in colorectal cancer.
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07/21/15
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