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Found 15815 articles
In vitro and in vivo single-agent efficacy of checkpoint kinase inhibition in acute lymphoblastic leukemia
Treatment with PF-00477736 showed efficacy ex vivo in primary leukemic blasts.
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11/05/15
Ascorbic acid and ascorbate-2-phosphate decrease HIF activity and malignant properties of human melanoma cells
Supplementation with both AA and A2P antagonized normoxic as well as cobalt chloride- and PHD inhibitor.
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11/07/15
Intermittent Versus Continuous Androgen Deprivation Therapy in Patients with Relapsing or Locally Advanced Prostate Cancer: A Phase 3b Randomised Study (ICELAND).
IAD and CAD demonstrated similar efficacy, tolerability, and QoL in men with nonmetastatic PCa.
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06/26/15
First line crizotinib in anaplastic lymphoma kinase (ALK) rearranged squamous cell lung cancer.
Question whether ALK testing should be done in never smokers with squamous NSCLC.
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05/06/15
Nicotine enhances invasion and metastasis of human colorectal cancer cells through the nicotinic acetylcholine receptor downstream p38 MAPK signaling pathway.
p38 MAPK may have potential as a therapeutic target for smoking-related human colorectal cancer metastasis.
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07/20/15
CKMT1 and NCOA1 expression as a predictor of clinical outcome in patients with advanced-stage head and neck squamous cell carcinoma.
Thirty genes were associated with local-recurrence or progression-free survival.
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07/30/15
Resveratrol induces cell cycle arrest in human gastric cancer MGC803 cells via the PTEN‑regulated PI3K/Akt signaling pathway.
Resveratrol did not decrease the phosphorylation level of Akt when the PTEN gene expression was knocked down by an siRNA.
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07/19/15
Clinical significance of Gremlin 1 in cervical cancer and its effects on cancer stem cell maintenance.
Gremlin 1 may have a role in clinical recurrence and maintaining CSC-like properties.
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08/06/15
Prospective evaluation of serum glial fibrillary acidic protein (GFAP) as a diagnostic marker for glioblastoma.
Serum GFAP levels in GBM patients were positively correlated with tumor volume and histopathological tumor characteristics.
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07/07/15
Inhibition of High Basal Level of Autophagy Induces Apoptosis in Human Bladder Cancer Cells.
Autophagy is required for growth and survival of human bladder cancer cells.
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10/16/15
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