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Found 15815 articles
AHNAK is downregulated in melanoma, predicts poor outcome, and may be required for the expression of functional cadherin-1.
Knockdown of AHNAK in primary melanocytes and in a keratinocyte cell line led to a reduction in detectable cadherin-1.
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12/18/15
Nsc23925 prevents the development of paclitaxel resistance by inhibiting the introduction of P-glycoprotein and enhancing apoptosis.
Combination of paclitaxel and NSC23925 therapy did not induce obvious toxicity.
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12/13/14
HER2 expression and markers of phosphoinositide-3-kinase pathway activation define a favorable subgroup of metastatic pulmonary adenocarcinomas.
Expression of HER2 and pAKT was associated with favorable overall survival in stage IV disease.
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10/01/14
Effects of Helicobacter pylori eradication on the development of metachronous gastric cancer after endoscopic treatment: analysis of molecular alterations by a randomised controlled trial.
H. pylori treatment may not prevent the development of MGC.
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09/19/15
External validation of sTWEAK as a prognostic noninvasive biomarker for head and neck squamous cell carcinoma.
Disease-free survival rate in patients with high sTWEAK was significantly higher.
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02/11/15
Resveratrol analogue (E)-8-acetoxy-2-[2-(3,4-diacetoxyphenyl)ethenyl]-quinazoline induces G₂/M cell cycle arrest through the activation of ATM/ATR in human cervical carcinoma HeLa cells.
8-ADEQ appears to have potential in the treatment of cervical cancer.
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12/01/14
Identification of the TP53-induced glycolysis and apoptosis regulator in various stages of colorectal cancer patients.
TIGAR expression may be used as a bio-marker for detection of colorectal cancer.
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10/13/15
5-Azacytidine inhibits the proliferation of bladder cancer cells via reversal of the aberrant hypermethylation of the hepaCAM gene.
AZAC may represent an effective treatment for bladder cancer.
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06/14/15
Deacetylation of tumor-suppressor MST1 in Hippo pathway induces its degradation through HBXIP-elevated HDAC6 in promotion of breast cancer growth.
HBXIP upregulated HDAC6 at the levels of mRNA and protein by activating transcription factor nuclear factor-κB.
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07/02/15
Choline Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target.
CHKA can act as an AR chaperone.
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01/12/15
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