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Found 15822 articles
IDH mutation is associated with higher risk of malignant transformation in low-grade glioma.
All IDHmut/MGMTmet subsets consistently showed higher risks of MT.
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02/27/15
miR-155 drives metabolic reprogramming of ER+ breast cancer cells following long-term estrogen deprivation and predicts clinical response to aromatase inhibitors.
Suppression of miR-155 resulted in sensitization of MCF7-LTED cells to metformin.
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01/23/16
Impact of Adjuvant Intravesical Bacillus Calmette-Guérin Treatment on Patients with High-Grade T1 Bladder Cancer.
Adjuvant intravesical BCG treatment was associated with decreased cancer-specific mortality.
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11/26/15
AXIN2 expression predicts prostate cancer recurrence and regulates invasion and tumor growth.
Low AXIN2 expression was associated with PCa recurrence after radical prostatectomy.
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06/14/15
Decreased expression of SIRT6 promotes tumor cell growth correlates closely with poor prognosis of ovarian cancer.
SIRT1 localizes to the promoters of several aberrantly silenced tumor suppressor genes whose DNA is hypermethylated.
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01/19/16
Overexpression of KIF23 predicts clinical outcome in primary lung cancer patients.
KIF23 transcript was found to be overexpressed in the great majority of metastatic lymph nodes from advanced lung cancers and primary lung tumors.
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08/15/15
MicroRNA-27b suppresses Helicobacter pylori-induced gastric tumorigenesis through negatively regulating Frizzled7.
Restoration of FZD7 expression significantly attenuated the inhibitory effect of miR-27b overexpression.
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11/03/15
Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin-GUCY2C Paracrine Signaling Axis.
Expression of guanylin in intestinal epithelial cells restored GUCY2C signaling.
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01/17/16
Hormone replacement therapy after menopause and risk of breast cancer in BRCA1 mutation carriers: a case-control study.
Short course of HRT should not be contra-indicated for BRCA1 mutation carriers.
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01/06/16
Epigenetic silencing of CREB3L1 by DNA methylation is associated with high-grade metastatic breast cancers with poor prognosis and is prevalent in triple negative breast cancers
Decreased CREB3L1 mRNA expression was associated with increased tumor grade and reduced progression-free survival.
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01/25/16
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