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Found 15822 articles
Neural stem cells, the subventricular zone and radiotherapy: implications for treating glioblastoma.
Neurogenesis and malignant transformation occurs in the subventricular zone adjacent to the lateral ventricles.
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12/18/15
NCOA3 coactivator is a transcriptional target of XBP1 and regulates PERK-eIF2α-ATF4 signalling in breast cancer.
Data identify XBP1-NCOA3 axis that regulates cell fate decisions in ER-positive breast cancer cells.
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10/24/15
Enhanced uptake and transport of PLGA-modified nanoparticles in cervical cancer.
A delivery strategy combining NPs with either modification may balance cellular internalization.
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01/28/16
Cyproheptadine exhibits antitumor activity in urothelial carcinoma cells by targeting GSK3β to suppress mTOR and β-catenin signaling pathways.
Cyproheptadine is a suitable therapeutic agent for the treatment of UC.
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06/02/15
TNF Receptor-2 Facilitates an Immunosuppressive Microenvironment in the Liver to Promote the Colonization and Growth of Hepatic Metastases.
Findings implicate TNFR2 in supporting MDSC-mediated immune suppression and metastasis in the liver.
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10/28/14
Progestins inhibit calcitriol-induced CYP24A1 and synergistically inhibit ovarian cancer cell viability: An opportunity for chemoprevention.
Show for the first time that progestins and vitamin D synergistically reduce cell viability and induce apoptosis in ovarian cells.
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11/09/15
Silencing of long non-coding RNA ANRIL inhibits the development of multidrug resistance in gastric cancer cells.
ANRIL knockdown decreased the expression of MDR1 and MRP1.
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12/25/15
Oridonin upregulates PTEN through activating p38 MAPK and inhibits proliferation in human colon cancer cells.
ORI also increases the phosphorylation of p38 MAPK.
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12/10/15
Use of tricyclic antidepressants and risk of glioma: a nationwide case-control study.
Long-term use of TCAs may be associated with a reduced risk of glioma.
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12/04/15
Expression of the chemokine CXCL14 in the tumour stroma is an independent marker of survival in breast cancer.
Correlation between stromal CXCL14 expression and survival was more prominent in ER negative, triple negative and basal-like breast cancers.
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02/04/16
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