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Found 15822 articles

Changes of Socio-demographic data of clients seeking genetic counseling for hereditary breast and ovarian cancer due to the “Angelina Jolie Effect”

Subjects were more frequent younger and higher educated. »
07/08/16

1-methylnicotinamide and its structural analog 1,4-dimethylpyridine for the prevention of cancer metastasis

Anti-metastatic activity of 1-MNA and 1,4-DMP was further confirmed when both agents were applied with a cytostatic drug. »
07/13/16

Inhibition of EZH2 via activation of SAPK/JNK and reduction of p65 and DNMT1 as a novel mechanism in inhibition of human lung cancer cells by polyphyllin I

PPI significantly inhibited growth and induced cell cycle arrest of non-small cell lung cancer. »
07/16/16

Bile acids destabilise HIF-1α and promote anti-tumour phenotypes in cancer cell models

Bile acids impaired cell adhesion, migration and invasion. »
07/14/16

Psychological stress, adverse life events and breast cancer incidence: a cohort investigation in 106,000 women in the United Kingdom

Positive association of divorce with estrogen-receptor-negative but not with estrogen-receptor-positive breast cancer. »
07/15/16

Clinicopathological features and prognosis of gastric cancer in young patients

The five-year overall survival rates were comparable between young patients and middle-aged patients. »
07/14/16

Metformin elicits antitumor effects and downregulates the histone methyltransferase multiple myeloma SET domain (MMSET) in prostate cancer cells.

siRNA-mediated knockdown of MMSET showed decreased cellular migration and invasion in DU-145 cells. »
12/25/15

Genome-wide association study confirms lung cancer susceptibility loci on chromosomes 5p15 and 15q25 in an African-American population.

Additional work is required to map and understand the biological underpinnings of the strong association of these loci with lung cancer risk. »
11/25/15

Hypoxia-regulated MicroRNAs in Gastroesophageal Cancer.

Expression of miR-210 was shown to be significantly induced in esophageal squamous cell carcinoma. »
02/07/16

Antitumor effects of minodronate, a third-generation nitrogen-containing bisphosphonate, in synergy with γδT cells in human glioblastoma in vitro and in vivo.

Combined intraperitoneal administration of MDA/GDT induced antitumor effects on unestablished U87MG-derived subcutaneous tumors. »
03/24/16

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