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Found 15822 articles
Superior efficacy and selectivity of novel small molecule kinase inhibitors of T790M mutant EGFR in preclinical models of lung cancer.
GNS-1486 showed superior potency against intracranial metastasis of EGFR-mutant lung adenocarcinoma.
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12/07/16
Homocysteinemia is Associated with a Lower Degree of PBMC LINE-1 Methylation and a Higher Risk of CIN 2C in the U.S. Post-Folic Acid Fortification Era.
Women with higher Hcy concentrations were at a greater risk of being diagnosed with CIN 2+.
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03/24/16
Neutrophil-to-lymphocyte ratio: Prognostic indicator for head and neck squamous cell carcinoma.
The interaction between NLR and HPV status suggests that HPV status may be a determining factor in the favorable prognosis.
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05/17/16
The role of histone modifications and telomere alterations in the pathogenesis of diffuse gliomas in adults and children.
These histone H3 mutations frequently co-occur with inactivating mutations in ATRX.
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08/10/16
The impact of preoperative anemia on oncologic outcome in patients undergoing radical cystectomy for urothelial carcinoma of the bladder.
Preoperative anemic bladder cancer patients who underwent RC had worse oncological outcomes.
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10/22/15
Expression of glia maturation factor γ is associated with colorectal cancer metastasis and its downregulation suppresses colorectal cancer cell migration and invasion in vitro.
GMFG should be further evaluated as a biomarker for detection of colorectal cancer metastasis.
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06/20/16
FBXO32 suppresses breast cancer tumorigenesis through targeting KLF4 to proteasomal degradation.
FBXO32 inhibits colony formation in vitro and primary tumor initiation and growth in vivo.
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04/14/16
Mesenchymal stem cells induce epithelial mesenchymal transition in melanoma by paracrine secretion of transforming growth factor-β.
Snail, as a downstream target of TGF-β signaling and an EMT regulator, was upregulated by MSC CM.
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01/13/17
Immediate chest X-ray for patients at risk of lung cancer presenting in primary care: randomised controlled feasibility trial.
The trial design and materials were acceptable to GPs and patients.
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05/16/16
NHERF1 Enhances Cisplatin Sensitivity in Human Cervical Cancer Cells.
NHERF1 overexpression in CaSki cells promoted cisplatin sensitivity.
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11/19/16
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