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Found 15815 articles
Regular and low-dose aspirin, other non-steroidal anti-inflammatory medications and prospective risk of HER2-defined breast cancer: the California Teachers Study
Reduced risk of breast cancer among participants who took three or more tablets of low-dose aspirin weekly.
»
05/01/17
Autophagy maintains the stemness of ovarian cancer stem cells by FOXA2.
Self-renewal ability was decreased in the case of FOXA2 knockdown by shRNA.
»
11/29/17
Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity
Weight loss in a group of obese mice reversed increases in progenitor activity.
»
11/29/17
JMJD6 promotes melanoma carcinogenesis through regulation of the alternative splicing of PAK1, a key MAPK signaling component
JMJD6 is transcriptionally activated by c-Jun, generating a feedforward loop.
»
11/29/17
Nanopore sequencing of full-length
BRCA1
mRNA transcripts reveals co-occurrence of known exon skipping events
Fourteen novel isoforms were formed entirely from a combination of previously identified alternative splice junctions.
»
11/29/17
Apigenin, by activating p53 and inhibiting STAT3, modulates the balance between pro-apoptotic and pro-survival pathways to induce PEL cell death
Regulatory loop between two pathways modulates PEL cell death/survival.
»
11/26/17
Histone profiling reveals the H1.3 histone variant as a prognostic biomarker for pancreatic ductal adenocarcinoma
Intratumor expression of H1.3 was found to be an important risk factor for overall survival in PDAC.
»
12/02/17
Tumor-infiltrating CD4
+
T cells in patients with gastric cancer
Combined PD-1+ and Tim-3+ inhibition had a synergistic effect on IFN-γ secretion.
»
12/02/17
Trastuzumab emtansine delays and overcomes resistance to the third-generation EGFR-TKI osimertinib in NSCLC EGFR mutated cell lines
HER-2 amplification was associated with osimertinib-resistance.
»
12/04/17
Increased expression of MARCH8, an E3 ubiquitin ligase, is associated with growth of esophageal tumor
Silencing of MARCH8 induced apoptosis.
»
12/04/17
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